Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity
نویسندگان
چکیده
منابع مشابه
Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity
TMEM16A and TMEM16B are plasma membrane proteins with Ca2+-dependent Cl- channel function. By replacing the carboxy-terminus of TMEM16A with the equivalent region of TMEM16B, we obtained channels with potentiation of channel activity. Progressive shortening of the chimeric region restricted the "activating domain" to a short sequence close to the last transmembrane domain and led to TMEM16A cha...
متن کاملRegulation of Rhogef Activity by Intramolecular and Intermolecular Sh3 Interactions
INTERMOLECULAR SH3 INTERACTIONS Martin R. Schiller, Kausik Chakrabarti, Glenn F. King, Noraisha I. Schiller, Betty A. Eipper, and Mark W. Maciejewski From the University of Connecticut Health Center, Departments of Neuroscience, Molecular, Microbial, and Structural Biology, and Center for Structural Biology Running Title: Regulation of GEF activity by SH3 domains Address correspondence to Marti...
متن کاملControlling intermolecular spin interactions of La@C(82) in empty fullerene matrices.
The ESR properties and crystal structures of solid-state La@C(82) in empty fullerene matrices were investigated by changing the concentration of La@C(82) and the species of an empty fullerene matrix: C(60), C(70), C(78)(C(2v)(3)), C(82)(C(2)) and C(84)(D(2d)(4)). The rotational correlation time of La@C(82) molecules tended to be shorter when La@C(82) is dispersed in larger fullerene matrices be...
متن کاملTerahertz laser spectroscopy of the water dimer intermolecular vibrations .
Terahertz laser VRT spectra of the water dimer consisting of 731 transitions measured with an average precision of 2 MHz and involving four ~D2O!2 intermolecular vibrations ~one previously published! have been measured between 65 and 104 cm. The precisely determined energy level patterns differ both qualitatively and quantitatively from the predictions of several dimer potentials tested, and re...
متن کاملTerahertz laser spectroscopy of the water dimer intermolecular vibrations . II
Terahertz VRT laser spectra of four ~H2O!2 intermolecular vibrations consisting of 362 transitions have been measured between 87 and 108 cm with ca. 2 MHz precision. The results differ both qualitatively and quantitatively from the predictions of dimer potentials tested. The spectra also reveal an ordering of the intermolecular vibrations which differs dramatically from that predicted by normal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep38788